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. 2015 Dec 29;10(12):e0146042. doi: 10.1371/journal.pone.0146042

Fig 5. Involvement of cAMP and PKA on STa modulation of J H+.

Fig 5

A, The overall transmembrane H+ flux rates (J H+) were calculated from initial rates of pHi recovery and the intrinsic buffer capacity (βi) values (see Methods). Cells were exposed to culture medium without (–, Control, red bar) or with (+) 10 μmol/L forskolin, 0.25 μmol/L heat-stable (STa) enterotoxin, 25 μmol/L HOE-694, and/or 100 nmol/L H89 (see Methods). B, cAMP levels in cells in the absence (Control) or presence of STa or forskolin as in A. In A, *P<0.05 versus Control, †P<0.05 versus STa, HOE-694, or STa + HOE-694. In B, *P<0.05 versus Control, †P<0.05 versus STa. Values are mean ± S.E.M. (n = 25–27).