Table 1.
Demographic and Clinical Characteristics of the Study Subjects
| Patient characteristics | Without triamterene | With triamterene | p values |
|---|---|---|---|
| N = 14,160 | N = 3131 | ||
| Age at first recorded hypertension diagnosis | 50.7 ± 13.4 | 50.8 ± 12.8 | 0.8282 |
| Female | 9253 (65.3 %) | 2405 (76.8 %) | < 0.0001 |
| Black race | 8107 (57.3 %) | 2085 (66.6 %) | < 0.0001 |
| Diabetes | 4709 (33.3 %) | 892 (28.5 %) | < 0.0001 |
| Chronic kidney disease | 1188 (8.4 %) | 250 (8 %) | 0.4575 |
| Coronary artery disease | 2024 (14.3 %) | 368 (11.8 %) | 0.0002 |
| Myocardial infarction | 670 (4.7 %) | 115 (3.7 %) | 0.0100 |
| Congestive heart failure | 1316 (9.3 %) | 214 (6.8 %) | < 0.0001 |
| Hyperlipidemia | 5433 (38.4 %) | 1230 (39.3 %) | 0.3406 |
| Atrial fibrillation | 567 (4 %) | 116 (3.7 %) | 0.4364 |
| Stroke | 641 (4.5 %) | 110 (3.5 %) | 0.0118 |
| Chronic obstructive pulmonary disease | 1940 (13.7 %) | 362 (11.6 %) | 0.0014 |
| Depression | 3184 (22.5 %) | 697 (22.3 %) | 0.7852 |
| Years since first hypertension treatment | 3.3 ± 4.2 | 3.1 ± 4.1 | 0.0720 |