Table 2.
Estimated Effects of Triamterene on Systolic BP by Drug Class: Hydrochlorothiazide (HCTZ), Angiotensin-converting enzyme (ACE) inhibitor, Beta-blocker (BB), Calcium channel blocker (CCB)
| Drug combinations | Number of patients who did not receive triamterene | Mean SBP of patients who did not receive triamterene (SD) | Number of patients who received triamterene | Mean SBP of patients who received triamterene (SD) | Estimated effect on systolic BP from propensity score analysis (SD) | p value |
|---|---|---|---|---|---|---|
| HCTZ | 1865 | 135.75 (14.40) | 498 | 131.32 (13.65) | 3.80 (0.70) | < 0.0001 |
| HCTZ + ACE | 1867 | 136.11 (14.61) | 255 | 132.91 (13.29) | 2.40 (1.15) | 0.0365 |
| HCTZ + ACE + CCB | 1174 | 142.24 (15.54) | 239 | 138.50 (13.66) | 2.97 (0.98) | 0.0024 |
| HCTZ + ACE + BB + CCB | 1228 | 143.15 (15.71) | 270 | 140.07 (14.04) | 3.50 (1.22) | 0.0039 |
| All drug combinations | 14,147 | 139.02 (15.23) | 3131 | 136.91 (14.69) | 1.84 (0.29) | < 0.0001 |