Table 1.
Baseline Clinical Characteristics of Study Subjects
| Characteristic | Nonsmokers (n = 11) | Smokers (n = 10) | COPD (n = 9) | P Values |
|---|---|---|---|---|
| Age, y | 62.18 ± 1.62 | 52.50 ± 2.23 | 60.44 ± 3.17 | < .05 SMK vs NS |
| Sex, male:female | 4:7 | 4:6 | 6:3 | NS |
| Current smokers | 0 | 10/10 | 8/9 | … |
| Smoking history, pack-years | 0 | 32.1 ± 3.02 | 39.44 ± 3.25 | NS |
| FEV1, L | 3.17 ± 0.17 | 3.24 ± 0.21 | 2.31 ± 0.13 | < .05 COPD vs NS < .01 COPD vs SMK |
| FEV1 % predicted | 102.2 ± 3.34 | 96.60 ± 3.28 | 68.11 ± 1.58 | < .0001 COPD vs SMK and NS |
| FEV1/FVC | 77.62 ± 1.09 | 78.04 ± 2.18 | 61.58 ± 1.80 | < .0001 COPD vs SMK and NS |
Data given as mean ± SEM. NS = nonsmoker; SMK = smoker.