Fig. 1.

Mean differences (a) and absolute differences (b) of each individual patient in the H/M ratios at 1, 2 and 3 h p.i. in comparison with H/M ratio at 4 h p.i. The mean difference with 95 % CI of H/M ratios of late ¹²³I-MIBG images with acquisition at 1, 2 and 3 h p.i. in comparison with the H/M ratio of the late ¹²³I-MIBG image at 4 h p.i. analysed with a linear mixed model (a). Each dot represents an absolute difference of each individual patient in the late H/M ratios at 1, 2 and 3 h p.i. compared with the late H/M ratio at 4 h p.i. (b). A mean difference in H/M ratio of more than 0.10 between the different acquisition times in comparison with the late H/M ratio at 4 h p.i. was considered clinically relevant