Table 1.
Characteristics of HCC Patients in the Training and Validation Cohort
| Variables | Training Set |
Validation Set |
|||
|---|---|---|---|---|---|
|
n = 344 |
n = 339 |
P |
|||
| No. | % | No. | % | ||
| Age (years) | .236 | ||||
| ≤ 50 | 164 | 47.7 | 177 | 52.2 | |
| > 50 | 180 | 52.3 | 162 | 47.8 | |
| Gender | .252 | ||||
| Male | 309 | 89.8 | 295 | 87.0 | |
| Female | 35 | 10.2 | 44 | 13.0 | |
| HBsAg | .467 | ||||
| Negative | 47 | 13.7 | 53 | 15.6 | |
| Positive | 297 | 86.3 | 286 | 84.4 | |
| AFP | .483 | ||||
| ≤ 25 ng/ml | 130 | 37.8 | 137 | 40.4 | |
| > 25 ng/ml | 214 | 62.2 | 202 | 59.6 | |
| Tumor number | .245 | ||||
| Single | 293 | 85.2 | 299 | 88.2 | |
| Multiple | 51 | 14.8 | 40 | 11.8 | |
| Tumor size | .504 | ||||
| ≤ 5 cm | 182 | 52.9 | 188 | 55.5 | |
| > 5 cm | 162 | 47.1 | 151 | 44.5 | |
| Macrovascular invasion | .206 | ||||
| Absent | 330 | 95.9 | 331 | 97.6 | |
| Present | 14 | 4.1 | 8 | 2.4 | |
| TNM stage | .055 | ||||
| I-II | 294 | 85.5 | 306 | 90.3 | |
| III-IV | 50 | 14.5 | 33 | 9.7 | |
| Tumor differentiation | .137 | ||||
| I-II | 222 | 64.5 | 202 | 59.6 | |
| III-IV | 118 | 34.3 | 136 | 40.1 | |
| Missing | 4 | 1.2 | 1 | 0.3 | |
| Child-Pugh classification | .830 | ||||
| A | 335 | 97.4 | 331 | 97.6 | |
| B | 9 | 2.6 | 8 | 2.4 | |
Note: The differences in the clinicopathological parameters between the training set and the validation set were evaluated using Mann-Whitney U two-independent-samples tests.