Table 2.
Association of Patient and PT Characteristics with HER2 Status and ER Status of DTCs Detected in BM Samples of 54 BC Patients
| HER2 Status of DTCs |
ER Status of DTCs |
||||||
|---|---|---|---|---|---|---|---|
| At Least One HER2-Positive DTC (n = 24) | No HER2-Positive DTC (n = 30) | P Value | At Least One ER-Positive DTC (n = 40) | No ER-Positive DTC (n = 14) | P Value | ||
| Menopausal status | Premenopausal | 7 | 8 | .839† | 11 | 4 | 1.000⁎ |
| Postmenopausal | 17 | 22 | 29 | 10 | |||
| pT | pT1 | 13 | 16 | .996† | 24 | 5 | .254† |
| pT2 | 8 | 10 | 11 | 7 | |||
| pT3 | 3 | 4 | 5 | 2 | |||
| pN | pN0 | 15 | 19 | .982† | 27 | 7 | .197⁎ |
| pN + | 8 | 10 | 11 | 7 | |||
| n/a | 1 | 1 | 2 | 0 | |||
| Histological grading | G1 | 1 | 4 | .486† | 5 | 0 | .059† |
| G2 | 14 | 17 | 25 | 6 | |||
| G3 | 9 | 9 | 10 | 8 | |||
| Histological type | Ductal | 17 | 23 | .889† | 27 | 13 | .164† |
| Lobular | 5 | 5 | 9 | 1 | |||
| Other | 2 | 2 | 4 | 0 | |||
| ER status | Negative | 5 | 7 | .826† | 6 | 6 | .031† |
| Positive | 19 | 23 | 34 | 8 | |||
| PR status | Negative | 8 | 12 | .614† | 12 | 8 | .070† |
| Positive | 16 | 18 | 28 | 6 | |||
| HER2 status | Negative | 22 | 26 | .682⁎ | 36 | 12 | .643⁎ |
| Positive | 2 | 4 | 4 | 2 | |||
⁎
Exact Fisher test.
†
Chi-square test (without unknowns).