Table 2.
Volumes of Anatomic Regions of Interest for All Subjects
| TMZ+enza Cohort |
TMZ+erl+bev Cohort |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Timepoint | Baseline | 1 mth | 2 mths | 4 mths | Baseline | 1 mth | 2 mths | 4 mths | |
| # Subjects | 39 | 29 | 38 | 27 | 29 | 25 | 25 | 27 | |
| T2 volume (cm3) | median | 20.6 | 22.4 | 18.5 | 17.6 | 26.5 | 24.2 | 10.4* | 11.9* |
| min | 3.5 | 4.9 | 3.4 | 4.2 | 1.7 | 2.3 | 0.1 | 0.3 | |
| max | 115.9 | 78.8 | 88.3 | 157.9 | 142.3 | 139.2 | 42.8 | 43.5 | |
| CE volume (cm3) | median | 6.3 | 4.1* | 3.3* | 1.9* | 2.8 | 1.2* | 0.7* | 0.2* |
| min | 0.0 | 0.6 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | |
| max | 29.6 | 19.1 | 29.5 | 20.8 | 21.9 | 17.6 | 8.7 | 3.5 | |
| T1S volume (cm3) | median | 7.3 | 5.2* | 4.0* | 2.8* | 6.3 | 3.7* | 1.1* | 0.9* |
| min | 2.7 | 1.7 | 0.7 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | |
| max | 52.6 | 20.5 | 37.3 | 74.6 | 37.9 | 29.9 | 8.7 | 7.6 | |
The asterisk denotes circumstances for which the change in volume from the baseline (pre-RT) value was significant based upon a Wilcoxon signed rank test.