The ER/PR scoring methods and criteria
|
Scoring methods |
0 |
Negative for ER/PR receptors |
1 |
Barely detected |
2+/3+ |
Positive for ER/PR receptors |
Criteria |
0 |
No or 0% nuclear staining |
1+ |
<15% or occasional nuclear staining (1–15%) |
2+ |
>15% to 75% clear positive nuclear staining |
3+ |
>75% positive staining |
Her2/Neu scoring method and criteria |
0 |
Negative. |
1+ |
Negative/very weakly positive. |
2+ |
Weakly sporadic positive |
3+ |
Positive |
Criteria |
0 |
0% or no staining was observed, negative staining. |
1+ |
Barely/very faint membranous staining but the staining did not reach more than 10%. |
2+ |
The staining intensity was weak, occasional membranous staining was observed, total positive staining tumor cells higher than 10%. |
3+ |
Strong consistent positive membranous staining in more than 10% of tumor cells. |