Table 5. Univariate and multivariate analysis of overall survival in breast cancer patients.

Characteristics	Univariate analysis		Multivariate analysis
	HR (95% CI)	p value	HR (95% CI)	p values
Age
<40	1*
>40	1.50(1.31–2.42)	0.016	1.40(1.41–2.41)	0.003
Shh	2.12(1.45–2.32)	0.021	1.34(1.02–1.78)	0.001
Tumor stage
pT1	1*		1*
pT3	2.034(1.87–2.97)	0.002	1.34(0.97–3.32)	0.01
pT4	2.24(2.18–5.23)	0.003	2.01(1.25–5.14)	0.001
pT4	3.41(3.21–6.31)	0.003	2.30(3.21–5.41)	0.02
Shh	1.43(1.21–2.34)	0.002	1.12(1.01–1.76)	0.001
Tumor grade
G1	1*		1*
G2	1.50(0.03–2.41)	0.008	1.02(0.31–2.61)	0.006
G3	2.07(1.01–3.28)	0.004	1.21(1.05–2.41)	0.003
Shh	1.45(1.02–1.87)	0.002	1.12(0.98–1.45)	0.005
Receptor status
Negative	1*		1*
Positive	1.21(1.01–2.21)	0.006	0.95(0.51–1.12)	0.002
Shh	1.31(1.02–1.62)	0.004	0.94(0.91–1.12)	0.003

1^* Grade 1 is regarded as reference category.