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. 2016 Jan 5;6:18751. doi: 10.1038/srep18751

Figure 4. PDK4 mediates FXR activation-induced cell proliferation and promotion of glycolysis.

Figure 4

(A) Cell proliferation of HepG2 cells when transfected with PDK4 siRNA or control siRNA (NC). (B) Relative abundance of major intracellular intermediates in glycolysis pathway in HepG2 cells when treated with PDK4 siRNA with or without the combined treatment of GW4064. Values are presented with mean ± SD (n = 6; *P < 0.05; ***P < 0.001).