Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 4;212(1):39–49. doi: 10.1083/jcb.201510063

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Jordan et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — PAR proteins protect against cytokinesis failure when formin activity is reduced. (A) RNAi depletion of cortical PAR proteins disrupts A-P polarity. (B and C) Depletion of cortical PAR proteins leads to cytokinesis failure in formin(ts) (B) but not myosin-II(ts) mutant embryos (C) at semipermissive temperature (n = 10, all conditions; mean ± SEM). (D) Schematic of cortical line scan used for analysis in E. The arrowhead points to the site of initial furrow formation. (E) The A-P polarity boundary, where PAR-2 levels start to increase relative to PAR-6 levels, coincides with the site of furrow onset (gray line; n = 10; mean ± SD). Bars, 10 µm. AO, anaphase onset; a.u., arbitrary units; b, background. cyk-1 = formin; nmy-2 = myosin-II.