Table 3.
Mobilization and Apheresis Results
Mobilization and Apheresis Results | Routine G+P (n=76) | JIT-P (n=60) | P-value |
---|---|---|---|
Peak peripheral blood CD34+ cell count (μ/L), mean/median (range) | 77.5/61.5 (5–389) | 33.1/29 (7–101) | <0.001 |
CD34+ cells × 106 cells/kg collected on day 1, mean/median (range) | 4.3/2.9 (0.2–14.4) | 2.4/2.1 (0.4–6.7) | 0.001 |
Total CD34+ cells × 106 /kg collected, mean/median (range) | 6.7/5.8 (0.2–22.2) | 4.8/4.5 (1.7–9.8) | 0.02 |
Total number of apheresis sessions, mean/median (range) | 2.2/2.0 | 2.4/2 | 0.06 |
Mobilization failures, N (%) | 4 (5.3%) | 2 (3.3%) | 0.69 |
Patients collecting ≥ 2 × 106 CD34+ cells/kg on day 1 N (%) | 54 (71%) | 34 (56.7%) | 0.09 |
Patients collecting ≥ 5 × 106 CD34+ cells/kg on day 1 N (%) | 49 (66.2%) | 21 (36.2%) | <0.001 |
Patients collecting ≥ 10 × 106 CD34+ cells/kg on day 1 N (%) | 4 (5.3%) | 0 (0%) | <0.001 |
Number of patients requiring > 1 apheresis sessions (%) | 61 (80.2%) | 54 (90%) | 0.34 |
Number of patients requiring >2 apheresis sessions (%) | 22 (28.9%) | 27(45%) | 0.53 |
Abbreviations: G+P, Granulocyte-colony stimulating factor with plerixafor; JIT-P, Just-intime-plerixafor, kg, kilogram.