Figure 3. Curcumin administration after disease progression suppresses photoreceptor neurodegeneration.

Curcumin administration only during adult stage suppressed photoreceptor neurodegeneration in pathogenic Httex1p Q93 (a,c,e) and Q48 flies (b,d,f) quantified at 7 day post eclosion. At least 200 ommatidia in 6 flies were examined per condition. Data was quantified as the number of rhabdomeres per ommatidium (c,d) and the distribution of the percent of ommatidia (e,f). Data analysis was performed using an analysis of variance (ANOVA) followed by Tukey’s post hoc test; values represent mean ± SEM (**p < 0.01; *p < 0.05, compared with control).