Table 3. Median survival time (MST) in months, by treatment, GPA, and number of metastases.
WBRT | WBRT + SRS | ||||
---|---|---|---|---|---|
|
|
||||
n | MST (95% CI) | n | MST (95% CI) | P value | |
Overall | 126 | 5.8 (4.7-6.8) | 126 | 5.7 (4.6-8.6) | .21 |
GPA <3.5 | 104 | 5.4 (3.3-6.3) | 101 | 5.0 (3.2-6.5) | .97 |
GPA 3.5-4.0 | 22 | 10.3 (5.3-19.4) | 25 | 21.0 (10.5-36.0 | .05 |
1 metastasis | 73 | 5.0 (3.0-6.2) | 70 | 6.6 (4.6-11.2) | .07 |
GPA <3.5 | 56 | 3.3 (2.2-5.3) | 52 | 5.4 (3.4-6.6) | .16 |
GPA 3.5-4.0 | 17 | 11.4 (4.7-23.1) | 18 | 21.0 (10.0-36.0) | .21 |
2-3 metastases | 52 | 6.7 (5.7-9.1) | 55 | 5.3 (2.7-9.0) | .92 |
GPA <3.5 | 47 | 6.5 (5.4-9.1) | 48 | 4.0 (2.5-7.9) | .26 |
GPA 3.5-4.0 | 5 | 8.9 (2.4-14.6) | 7 | 14.1 (1.7-36.0) | .10 |
Abbreviations: CI = confidence interval; GPA = graded prognostic assessment; SRS = stereotactic radiosurgery; WBRT = whole-brain radiation therapy.