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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Alcohol Clin Exp Res. 2016 Jan;40(1):83–92. doi: 10.1111/acer.12940

Figure 4. EtOH-induced potentiation of tonic currents is TTX-sensitive in pre-weanlings.

Figure 4

Exemplar traces of the effect of TTX on (A) tonic currents and (B) sIPSC frequency and amplitude. (C) TTX significantly decreased tonic current amplitude (* - p < 0.05 compared to 0) and sIPSC frequency in pre-weanlings (** - p <0.001). (D) The significant EtOH (80 mM)-induced potentiation of tonic currents was abolished in the presence of TTX (* - p < 0.05 compared to 0). (E) The significant EtOH (80 mM)-induced increase of sIPSC frequency was abolished in the presence of TTX (* - p < 0.05 compared to 0). TTX – tetrodotoxin.