. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Alcohol Clin Exp Res. 2016 Jan;40(1):93–101. doi: 10.1111/acer.12929

TABLE 3.

Combined effects of the SLC6A1 functional indel promoter polymorphism and GABBR1 rs29220 on alcohol dependence in the African American sample of men and women

SLC6A1 IND + GABBR1 rs29220	M+F all AD N (freq)	M+F controls N (freq)	Fold increase

IND/CC	18 (0.071)	60 (0.139)	1.96
IND/GG	7 (0.028)	25 (0.058)	2.07
N/GG	23 (0.091)	58 (0.134)	1.47

total	48 (0.190)	143 (0.331)	1.74


IND/CG	29 (0.115)	38 (0.088)	1.31
N/CC	89 (0.353)	130 (0.301)	1.17
N/CG	86 (0.341)	121 (0.280)	1.22

total	204 (0.809)	289 (0.669)	1.22

The SLC6A1 promoter indel polymorphism is coded as IND (insertion polymorphism, minor allele), N (major allele) and GABBR1 rs29220 genotypes are coded as CC, CG, GG, where allele G is the minor allele.

All AD = total group of patients with alcohol dependence; controls have no addiction