Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 5;13:1. doi: 10.1186/s12974-015-0467-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Kim et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — HFD induced acute liver pathology and inflammation in WT and APP-Tg and mice. a Representative images of livers from WT or APP-Tg mice fed with HFD or SD, with corresponding liver and body weights of their respective age-matched SD-fed controls. Scale bar indicates 5 mm (b). ** and *** indicate p < 0.01 and p < 0.001, respectively (two-way ANOVA with Bonferroni post-test). c Representative CD45⁺ staining of liver sections from WT or APP-Tg mice fed with SD or HFD for 2 months. d Representative oil O-red staining on frozen tissue sections of livers from WT or APP-Tg mice fed with SD or HFD for 2 months. e Relative positive pixel count of oil O-red staining quantified using Zen software (Carl Zeiss). * and *** indicate p < 0.05 and p < 0.001, respectively (two-way ANOVA with Bonferroni post-test). f Quantitative analysis of total leukocyte numbers (CD45⁺) isolated from the livers of 2-month SD or HFD-fed WT and APP-Tg mice by flow cytometry. ** indicates p < 0.01 (two-way ANOVA with Bonferroni post-test, n = 3/group). g TNF-α, IL-6, and IL-17 mRNA expression in livers of WT and APP-Tg mice fed with SD or HFD for 2 months. ** indicates p < 0.01 (two-way ANOVA with Bonferroni post-test, n = 3/group, representative experiment of four independent experiments)