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. 2016 Jan 5;15:7. doi: 10.1186/s12936-015-1049-9

Table 3.

Reported minimum steady-state values Css (min) for sulfamethoxazole (SMX) and trimethoprim (TMP) in previous studies

SMX (mg ml−1) TMP (mg ml−1) References
23.8 2.2 Present study
45.5a 2.2a Kremers et al. [32]
35.6 1.5 Nowak et al. [31]
43.4 2.98 Kaplan et al. [30]

aPlasma concentration converted to whole blood equivalents using blood/plasma ratio [39]