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. 2016 Jan 4;16:1. doi: 10.1186/s12872-015-0179-x

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© Zhao et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Interleukin 2 (IL-2) increased the sodium current density dependent on SCN3B. a Representative traces for sodium currents without (left) and with (right) treated by IL2were elicited with the current protocol depicted in the inset. b. I-V relation for peak sodium current Nav1.5. Average Nav1.5 sodium current density is greater by treatment of IL2 in the presence of SCN3B. c Histogram of sodium current densities at −20 mV. Means and SEM: Control (−260.6 and 28.1 pF/pA n = 17), IL2 (−355.9 and 28.3 pF/pA n = 21).*p < 0.05