Fig. 4.

Interleukin 2 (IL-2) failed to increase the sodium current density in the absence of SCN3B. a Representative traces for sodium currents without (left) and with (right) treated by IL-2 were elicited with the current protocol depicted in the inset. b. I-V relation for peak sodium current Nav1.5. Average Nav1.5 sodium current density is similar between with and without IL-2 in the absence of SCN3B. c Histogram of sodium current densities at −20 mV. Means and SEM: Control (−354.7 and 41.7 pF/pA n = 20), IL2 (−361.0 and 35.3 pF/pA n = 17). NS = Not Significant