Table 1.
Baseline Characteristics
| Characteristic | Ischemic | Nonischemic | P Value |
|---|---|---|---|
| No. patients | 5185 | 3358 | |
| Age, y | 77.0±9.9 | 77.9±11.3 | <0.001 |
| Hypertension | 2601 (50.2) | 1475 (43.9) | <0.001 |
| Hyperlipidemia | 1260 (24.3) | 257 (7.7) | <0.001 |
| Diabetes | 2020 (39.0) | 981 (29.2) | <0.001 |
| Smoking history | 1991 (38.4) | 1096 (32.6) | <0.001 |
| Cerebrovascular disease | 1012 (19.5) | 485 (14.4) | <0.001 |
| Peripheral vascular disease | 885 (17.1) | 310 (9.2) | <0.001 |
| Dialysis | 75 (1.4) | 48 (1.4) | 0.948 |
| Chronic obstructive lung disease | 978 (18.9) | 575 (17.1) | 0.042 |
| Atrial fibrillation | 1633 (31.5) | 955 (28.4) | 0.003 |
| HFrEF | HFpEF | ||
|---|---|---|---|
| No. patients | 2448 | 1190 | |
| Age, y | 74.6±10.4 | 77.9±9.8 | <0.001 |
| Hypertension | 1187 (48.5) | 667 (56.1) | <0.001 |
| Hyperlipidemia | 583 (23.8) | 178 (15.0) | <0.001 |
| Diabetes | 926 (37.8) | 384 (32.3) | 0.001 |
| Smoking history | 1085 (44.3) | 433 (36.4) | <0.001 |
| Cerebrovascular disease | 398 (16.3) | 207 (17.4) | 0.388 |
| Peripheral vascular disease | 405 (16.5) | 140 (11.8) | <0.001 |
| Dialysis | 23 (0.9) | 13 (1.1) | 0.622 |
| Chronic obstructive lung disease | 381 (15.6) | 225 (18.9) | 0.001 |
| Atrial fibrillation | 690 (28.2) | 448 (37.6) | <0.001 |
| Men | Women | ||
|---|---|---|---|
| No. patients | 4133 | 4410 | |
| Age, y | 75.2±10.6 | 79.4±9.9 | <0.001 |
| Hypertension | 1811 (43.8) | 2265 (51.4) | <0.001 |
| Hyperlipidemia | 843 (20.4) | 674 (15.3) | <0.001 |
| Diabetes | 1554 (37.6) | 1447 (32.8) | <0.001 |
| Smoking history | 2012 (48.7) | 1075 (24.4) | <0.001 |
| Cerebrovascular disease | 714 (17.3) | 783 (17.8) | 0.56 |
| Peripheral vascular disease | 737 (17.8) | 458 (10.4) | <0.001 |
| Dialysis | 70 (1.7) | 53 (1.2) | 0.056 |
| Chronic obstructive lung disease | 859 (20.8) | 694 (15.7) | <0.001 |
| Atrial fibrillation | 1238 (30.0) | 1350 (30.6) | 0.508 |
Data are presented as mean±SD or n (%). HFrEF indicates heart failure with reduced ejection fraction; HFpEF, heart failure with preserved ejection fraction.