TABLE 1.
Demographic, Behavioral, and Self-report Variables in a Study of the Association Between Mineralocorticoid receptor Genotype, Childhood Neglect, and Amygdala reactivitya
| Iso/Iso Homozy- gotes (N=193) |
Val Carriers (N=86) | Analysis | Total Sample (N=279) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Variable | N | % | N | % | χ 2 | df | p | N | % |
|
| |||||||||
| Sex (female) | 95 | 49.22 | 45 | 52.32 | 0.23 | 1 | 0.63 | 140 | 50.18 |
| Race | |||||||||
| Caucasian | 114 | 59.07 | 44 | 51.16 | 1.51 | 1 | 0.22 | 158 | 56.63 |
| Hispanic | 65 | 33.68 | 38 | 44.19 | 2.82 | 1 | 0.09 | 103 | 36.92 |
| Other | 14 | 7.25 | 4 | 4.65 | 0.67 | 1 | 0.41 | 18 | 6.45 |
|
| |||||||||
| Mean | SD | Mean | SD | t | df | p | Mean | SD | |
|
| |||||||||
| Age (years) | 13.64 | 0.99 | 13.48 | 0.98 | 1.29 | 277 | 0.20 | 13.59 | 0.99 |
| Pubertal status (Tanner stage) | 3.56 | 1.00 | 3.36 | 0.96 | 1.55 | 277 | 0.12 | 3.50 | 0.99 |
| Childhood Trauma Questionnaire scores | |||||||||
| Emotional neglect | 8.40 | 3.67 | 7.77 | 2.76 | 1.44 | 277 | 0.15 | 8.21 | 3.43 |
| Emotional abuse | 7.60 | 3.17 | 6.99 | 2.41 | 1.60 | 277 | 0.11 | 7.41 | 2.96 |
| Physical neglect | 6.19 | 1.76 | 6.14 | 1.68 | 0.21 | 277 | 0.84 | 6.17 | 1.73 |
| Physical abuse | 6.30 | 1.94 | 6.10 | 1.73 | 0.79 | 277 | 0.43 | 6.24 | 1.88 |
| Sexual abuse | 5.13 | 0.63 | 5.20 | 0.73 | 0.79 | 277 | 0.43 | 5.15 | 0.66 |
| Face matching accuracy (%) | 98.82 | 5.02 | 99.28 | 2.70 | 0.78 | 255 | 0.44 | 0.99 | 0.04 |
| Face matching reaction time (ms) | 1,369 | 313 | 1,387 | 263 | 0.44 | 255 | 0.66 | 1,374 | 298 |
| Shape matching accuracy (%) | 97.01 | 7.54 | 98.19 | 4.47 | 1.31 | 255 | 0.19 | 0.97 | 0.07 |
| Shape matching reaction time (ms) | 1,223 | 249 | 1,239 | 216 | 0.49 | 255 | 0.63 | 1,228 | 239 |
a
Test statistics represent results from comparisons between iso homozygotes and val carriers. Behavioral data were available only for 257 participants because of technical difficulties with the equipment used to collect behavioral responses during fMRI.