Figure 5.

mRNA levels of Alzheimer's disease-related genes in differentiated SH-SY5Y neuroblastoma cells induced with 250 μM hydrogen peroxide (H₂O₂), with or without pretreatment with germinated brown rice (GBR) at 1 ppm and 10 ppm, respectively. Different letters on bars representing different groups indicating significant difference (p < 0.05). ADAM10: a disintegrin and metalloproteinase domain-containing protein 10; APP: amyloid precursor protein; BACE: beta-site APP-cleaving enzyme; LRP: low density lipoprotein receptor-related protein.