Table 4.
Effects of HRG on serum, liver and fecal metabolites
| Variable | Group | |
|---|---|---|
|
| ||
| HF | HF+HRG | |
| Serum lipids | ||
| Triacylglycerol (mmol/L) | 0.96±0.12 | 0.81±0.05 |
| Total cholesterol (mmol/L) | 2.68±0.15 | 2.45±0.07 |
| LDL-cholesterol (mmol/L)1) | 1.60±0.11 | 1.37±0.06 |
| HDL-cholesterol (mmol/L) | 1.46±0.10 | 1.49±0.07 |
| Atherogenic index (AI)2) | 0.81±0.08 | 0.70±0.07 |
| HDL/TC ratio | 0.56±0.02 | 0.60±0.02 |
| Liver lipids | ||
| Triacylglycerol (μmol/g) | 9.71±0.40 | 9.20±0.65 |
| Total cholesterol (μmol/g) | 3.08±0.28 | 3.01±0.22 |
| Total lipid (mg/g) | 31.75±0.97 | 31.22±1.49 |
| Fecal lipids | ||
| Triacylglycerol (μmol/d) | 5.85±0.67 | 6.66±0.76 |
| Total cholesterol (μmol/d) | 17.36±0.84 | 16.49±0.73 |
| Total lipid (mg/d) | 78.59±5.55 | 85.18±4.51 |
| Serum AST (IU/L) | 49.67±2.38 | 50.16±3.02 |
| Serum ALT (IU/L) | 12.41±1.18 | 12.40±0.89 |
| Leptin (ng/mL) | 9.75±0.89 | 7.18±0.51* |
Results are expressed as mean±SEM.
HF, high fat; HRG, high hydrostatic pressure extracts of red ginseng; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TC, total cholesterol; AST, aspartate transaminase; ALT, alanine transaminase.
1)
LDL-C=TC –HDL-C –(TG / 5).
2)
AI=(TC –HDL-C) / HDL-C.
*
P<0.05.