Figure 1.

Colonization of mice by IP delivery of SGD-K or SGD-C mutant libraries. Groups of BALB/c mice (6–10 week old female) were infected by the IP route with ~6 × 10⁶ CFU of the SGD-K (A, left panel) or the SGD-C (B, right panel) mutant library in 200 μl PBS. Mice were sacrificed 2 days post infection; spleen and liver were removed, weighed, homogenized, and CFU counts were evaluated. Input values are the average number of bacteria inoculated into each animal.