Table 1. Incidences and clinical characteristics of hospital discharges due to ischemic stroke among men with and without type 2 diabetes in Spain, 2003–2012.
| 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NO DIABETES | |||||||||||
| N | 12159 | 12345 | 12471 | 14791 | 15740 | 16692 | 16828 | 17293 | 17308 | 17524 | 153151 |
| Incidence* | 74.68 | 75.83 | 74.49 | 85.98 | 91.5 | 95.83 | 95.43 | 98.06 | 99.02 | 100.26 | 89.38 |
| Age, mean (SD)* | 70.74(12.51) | 70.95(12.4) | 71.09(12.76) | 71.18(12.95) | 71.19(13.08) | 71.34(13.17) | 71.28(13.28) | 71.48(13.35) | 71.10(13.50) | 71.46(13.51) | 71.21(13.11) |
| 15–44 years n (%)* | 433(3.56) | 397(3.22) | 480(3.85) | 553(3.74) | 620(3.94) | 622(3.73) | 653(3.88) | 638(3.69) | 687(3.97) | 656(3.74) | 5739(3.75) |
| 45–54 years n (%)* | 921(7.57) | 938(7.6) | 932(7.47) | 1166(7.88) | 1306(8.3) | 1386(8.3) | 1455(8.65) | 1506(8.71) | 1570(9.07) | 1642(9.37) | 12822(8.37) |
| 55–64 years n (%)* | 1805(14.84) | 1989(16.11) | 1914(15.35) | 2255(15.25) | 2380(15.12) | 2632(15.77) | 2586(15.37) | 2704(15.64) | 2790(16.12) | 2682(15.3) | 23737(15.5) |
| 65–74 years n (%)* | 3708(30.5) | 3528(28.58) | 3362(26.96) | 3909(26.43) | 3967(25.2) | 4033(24.16) | 3991(23.72) | 4029(23.3) | 3956(22.86) | 3880(22.14) | 38363(25.05) |
| 75–84 years n (%)* | 4013(33) | 4140(33.54) | 4366(35.01) | 5032(34.02) | 5380(34.18) | 5598(33.54) | 5704(33.9) | 5681(32.85) | 5686(32.85) | 5832(33.28) | 51432(33.58) |
| >84 years n (%)* | 1279(10.52) | 1353(10.96) | 1417(11.36) | 1876(12.68) | 2087(13.26) | 2421(14.5) | 2439(14.49) | 2735(15.82) | 2619(15.13) | 2832(16.16) | 21058(13.75) |
| CCI 0–1, n (%)* | 7303(60.06) | 7288(59.04) | 7415(59.46) | 8889(60.1) | 9600(60.99) | 9768(58.52) | 9790(58.18) | 9833(56.86) | 8895(51.39) | 8736(49.85) | 87517(57.14) |
| CCI 2, n (%)* | 4682(38.51) | 4881(39.54) | 4894(39.24) | 5683(38.42) | 5923(37.63) | 6596(39.52) | 6740(40.05) | 7089(40.99) | 7979(46.1) | 8315(47.45) | 62782(40.99) |
| CCI ≥3, n (%)* | 174(1.43) | 176(1.43) | 162(1.3) | 219(1.48) | 217(1.38) | 328(1.97) | 298(1.77) | 371(2.15) | 434(2.51) | 473(2.7) | 2852(1.86) |
| Atrial fibrillation, n (%)* | 2447(20.13) | 2485(20.13) | 2591(20.78) | 3025(20.45) | 3137(19.93) | 3619(21.68) | 3640(21.63) | 3926(22.7) | 3993(23.07) | 4128(23.56) | 32991(21.54) |
| Hypertension n (%)* | 5671(46.64) | 5875(47.59) | 6002(48.13) | 7128(48.19) | 7645(48.57) | 8336(49.94) | 8466(50.31) | 8847(51.16) | 8808(50.89) | 8874(50.64) | 75652(49.4) |
| Smoking n (%)* | 3987(32.79) | 4252(34.44) | 4230(33.92) | 5315(35.93) | 5300(33.67) | 5792(34.7) | 6169(36.66) | 6301(36.44) | 6505(37.58) | 6427(36.68) | 54278(35.44) |
| DIABETES | |||||||||||
| N | 4771 | 5080 | 5375 | 6221 | 6995 | 7572 | 7684 | 7934 | 8268 | 8367 | 68267 |
| Incidence* | 492.26 | 524.15 | 505.69 | 537.87 | 604.79 | 640.24 | 635.69 | 656.37 | 581.94 | 588.91 | 580.69 |
| Age, mean (SD)* | 70.65(9.89) | 70.93(10.05) | 71.03(10.13) | 71.26(10.39) | 71.55(10.25) | 71.54(10.54) | 71.75(10.66) | 71.92(10.86) | 72.02(10.82) | 72.12(10.75) | 71.57(10.51) |
| 15–44 years n (%)* | 54(1.13) | 41(0.81) | 47(0.87) | 58(0.93) | 57(0.81) | 70(0.92) | 78(1.02) | 89(1.12) | 69(0.83) | 74(0.88) | 637(0.93) |
| 45–54 years n (%)* | 250(5.24) | 302(5.94) | 321(5.97) | 380(6.11) | 385(5.5) | 482(6.37) | 477(6.21) | 501(6.31) | 532(6.43) | 483(5.77) | 4113(6.02) |
| 55–64 years n (%)* | 874(18.32) | 933(18.37) | 980(18.23) | 1095(17.6) | 1268(18.13) | 1336(17.64) | 1330(17.31) | 1363(17.18) | 1408(17.03) | 1464(17.5) | 12051(17.65) |
| 65–74 years n (%)* | 1810(37.94) | 1780(35.04) | 1844(34.31) | 2066(33.21) | 2221(31.75) | 2330(30.77) | 2293(29.84) | 2287(28.83) | 2367(28.63) | 2380(28.45) | 21378(31.32) |
| 75–84 years n (%)* | 1478(30.98) | 1674(32.95) | 1826(33.97) | 2135(34.32) | 2477(35.41) | 2675(35.33) | 2754(35.84) | 2833(35.71) | 3014(36.45) | 3018(36.07) | 23884(34.99) |
| >84 years n (%)* | 305(6.39) | 350(6.89) | 357(6.64) | 487(7.83) | 587(8.39) | 679(8.97) | 752(9.79) | 861(10.85) | 878(10.62) | 948(11.33) | 6204(9.09) |
| CCI 0–1, n (%)* | 2807(58.83) | 3001(59.07) | 3100(57.67) | 3673(59.04) | 4130(59.04) | 4303(56.83) | 4398(57.24) | 4269(53.81) | 4039(48.85) | 3930(46.97) | 37650(55.15) |
| CCI 2, n (%)* | 1902(39.87) | 2017(39.7) | 2182(40.6) | 2458(39.51) | 2755(39.39) | 3151(41.61) | 3107(40.43) | 3511(44.25) | 4018(48.6) | 4173(49.87) | 29274(42.88) |
| CCI ≥3, n (%)* | 62(1.3) | 62(1.22) | 93(1.73) | 90(1.45) | 110(1.57) | 118(1.56) | 179(2.33) | 154(1.94) | 211(2.55) | 264(3.16) | 1343(1.97) |
| Atrial fibrillation n (%)* | 730(15.3) | 792(15.59) | 935(17.4) | 986(15.85) | 1146(16.38) | 1297(17.13) | 1382(17.99) | 1437(18.11) | 1577(19.07) | 1706(20.39) | 11988(17.56) |
| Hypertension n (%)* | 2723(57.07) | 3089(60.81) | 3278(60.99) | 3883(62.42) | 4435(63.4) | 4800(63.39) | 4985(64.88) | 5132(64.68) | 5353(64.74) | 5443(65.05) | 43121(63.17) |
| Smoking n (%)* | 1445(30.29) | 1571(30.93) | 1804(33.56) | 1990(31.99) | 2257(32.27) | 2530(33.41) | 2644(34.41) | 2805(35.35) | 2922(35.34) | 2949(35.25) | 22917(33.57) |
N: Number of discharges; Incidence: per 100,000 inhabitants; CCI (Charlson Comorbidity Index): Comorbidities included in the Charlson comorbidity index, except diabetes and stroke.
* P<0.05 (Comparison by year: Poisson regression model for incidence rates, ANOVA for means, Kruskal-Wallis for medians, Pearson´s chi-square for proportions).