Fig. 2.

Model for epidermis cell fate specification. The TTG1/GL3/EGL3/WER complex directly activates expression of GL2 and CPC in atrichoblast cells (in light blue). CPC moves circumferentially to neighbouring cells, there outcompetes WER in binding to TTG1/GL3/EGL3 and results in the downregulation of GL2 and promotion of hair cell identity (trichoblast in dark blue). JKD and SCM provide positional cues from the underlying cortex cell layer by repressing WER and tipping the balance in favour of trichoblast cell fate.