Table 1. Differential gene expression in normal and cancer ovarian tissues.
Analysis of experimental data was carried out according to the Fischer exact test
| Gene | Method | Cutoff* | High expression# | Low expression# | P |
|---|---|---|---|---|---|
| SCD1 | RT-PCR | 1.04 | Normal: 2 Cancer: 11 |
Normal: 8 Cancer: 4 |
0.0154 |
| RT-qPCR | 30.00 | Normal: 2 Cancer: 14 |
Normal: 6 Cancer: 1 |
0.0017 | |
| DHCR7 | RT-qPCR | 0.27 | Normal: 7 Cancer: 4 |
Normal: 1 Cancer: 11 |
0.0094 |
| PDE8B | RT-PCR | 0.85 | Normal: 6 Cancer: 2 |
Normal: 4 Cancer: 13 |
0.0280 |
| SREBF2 | RT-PCR | 0.07 | Normal: 8 Cancer: 3 |
Normal: 2 Cancer: 12 |
0.0051 |
| SREBF1c | RT-qPCR | 0.40 | Normal: 2 Cancer: 10 |
Normal: 6 Cancer: 5 |
0.0894 |
*
Cutoff values were arbitrarily set and correspond to ratio of gene of interest expression against the reference gene expression.
#
High/low expression indicates values higher or lower than the cutoff.