Table 1. Clinicopathologic characteristics by CRBP-1 expression and factors influencing survival in lung adenocarcinoma patients.

	Total Number	CRBP-1 expression
		Low (%)	High (%)
Variable *	167 (%)	63 (37.7)	104 (62.3)	P
Sex
male	128 (76.6)	48	80	0.91
female	39 (23.4)	15	24
Age
< 67 years	85 (50.9)	32	53	0.98
> 67 years	82 (49.1)	31	51
Smoking status
current or former smokers	138 (82.6)	40	98	0.001
no-smokers	29 (17.4)	23	6
Histologic grade
G1	18 (10.8)	13	5	0.001
G2+G3	149 (89.2)	50	99
pT
T1+T2	134 (80.2)	49	85	0.37
T3+T4	33 (19.8)	14	19
Disease stage
I	112 (65.6)	43	69	0.37
II+III+IV	55 (34.4)	20	35

Variable **	P	HRa	95% Clb
CRBP-1	0.02	0.43	0.21-0.89
EGFR	0.001	3.18	0.67-6.05
CRABP-2	0.13	1.61	0.86-3.00
Ki-67	0.3	0.72	0.38-1.33
RARβ	0.09	0.58	0.31-1.08
RARα	0.68	0.87	0.45-1.69
Smokers/CRBP-1High	0.07	0.50	0.64-1.06
Coexpression EGFR/CRBP-1	0.24	0.56	0.21-1.46

^*χ2 test was used for relationships;

^**Multivariate Cox Regression Model;

^aHazard Ratio;

^bConfidence Interval