The similarity of large Tag sequences among different polyomaviruses is shown. Note that SV40 (simian virus 40) Tag is more closely related to those of JCV (JCPyV, JC polyomavirus), SA12 (simian agent virus 12), and BKV (BKPyV, BK polyomavirus) than to the Tags of other polyomaviruses: KIV (KIPyV, KI polyomavirus), WUV (WUPyV, WU polyomavirus), HPyV11/STLPyV (human polyomavirus 11), HPyV10 (human polyomavirus 10), HPyV7 (human polyomavirus 7), HPyV6 (human polyomavirus 6), HPyV9 (human polyomavirus 9), LPV/AGMPyV (B-lymphotropic polyomavirus), TSV (TSPyV, Trichodysplasia spinulosa-associated polyomavirus), MCPyV (Merkel cell polyomavirus), HPyV12 (human polyomavirus 12), and NJPyV (New Jersey polyomavirus, not shown) (http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id510624).