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. 2016 Jan 5;11(1):e0146432. doi: 10.1371/journal.pone.0146432

Fig 4. Statin reduces H. pylori-induced elongation of gastric epithelial cells.

Fig 4

(A) AGS cells were pretreated with simvastatin (25 μM) and infected with H. pylori at an MOI of 100 for 6 h. (B) The proportion of cells with the elongated (hummingbird) phenotype was evaluated as described in the materials and methods section. The quantitative results represent the means and standard deviations for three independent experiments. *, P < 0.05, compared with H. pylori-infected cells without simvastatin pretreatment. Scale bar, 10 μm.