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. 2016 Jan 5;11(1):e0145545. doi: 10.1371/journal.pone.0145545

Table 2. TTEST analyses within groups.

Delta Ct IGFBP3 Delta Ct F3 log(PSA)a Age, year Gleason score Tumor stage
RA
 Mean 3.46 1.55 1.00 67.07 6.74 1.77
 STD 1.94 1.90 0.37 7.75 0.90 0.78
 N 49 49 54 54 53 53
 TTESTb, P
  RA vs. PCa 0.5271 0.0026* <0.0001* 0.0002* <0.0001* <0.0001*
  RA vs. OD 0.0044* 0.0255* 0.0290* <0.0001* 0.1633 0.7100
  RA vs. MA 0.0008* 0.0280* 0.1451 0.0150* 0.0158* 0.8100
MA
 Mean 4.74 2.59 1.12 70.98 7.21 1.81
 STD 1.86 2.76 0.46 9.16 1.14 0.82
 N 57 57 63 63 61 63
 TTESTb, P
  MA vs. PCa <0.0001* 0.2786 <0.0001* 0.1750 <0.0001* <0.0001*
  MA vs. OD 0.8033 0.9186 0.5972 0.0018* 0.2346 0.8888
OD
 Mean 4.65 2.54 1.16 76.01 6.98 1.83
 STD 2.18 2.48 0.37 8.23 0.96 0.83
 N 55 55 58 60 59 59
 TTESTb, P
  OD vs. PCa 0.0002* 0.2290 0.0001* 0.0794 <0.0001* <0.0001*
PCa
 Mean 3.24 3.21 1.58 73.21 8.10 2.75
 STD 1.77 3.35 0.69 9.28 1.07 0.72
 N 61 61 61 64 62 63
 TTESTb, P
  MA vs. [OD+PCa] 0.0113* 0.5234 0.0031* 0.0100* 0.0636 0.0004*

Abbreviations: PCa: Death due to prostate cancer; OD: Death due to other causes; MA: Matched alive patients lived more than 5 years; RA: Randomly selected alive patients lived more than 5 years.

a PSA levels in serum were measured at the time of diagnosis (before treatment).

b TTEST analyses have been performed in two-tailed. P values are calculated within two groups, if P<0.05, this is marked with a star.