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. 2016 Jan 5;11(1):e0146337. doi: 10.1371/journal.pone.0146337

Table 2. Liver pathology scores.

Parameter BD AMLN SGLT2I
Steatosis 0 3.0* 2.4±0.6*
Lobular Inflammation 0 1.8±0.8* 0.8±0.8*
Hepatocyte Ballooning 0 0.2±0.4 0
NAS 0 5.0±0.7* 3.2±0.8*
Fibrosis stage 0 1.6±0.5* 0.8±0.4*

NAFLD activity score (NAS) and fibrosis stage were scored according to the method described by Kleiner et al. [27], as outlined in S1 Table. NAS, NAFLD Activity Score. Data are the mean ± SD (n = 5 each). Significance was determined using the Student’s t-test:

* p<0.05 versus BD mice

p<0.05 versus AMLN mice