Figure 2. No difference in Lrp1 expression in capillary-depleted brain fractions of Lrp1_BE^–/– and Lrp1_BE^fl/fl mice.

(A) Immunostaining of LRP1 α chain and β chain in brain fractions deprived of capillaries. An anti–β-actin immunoblot is shown as a loading control. MEF, mouse embryonic fibroblast. (B and C) Quantification of relative abundance of (B) LRP1 α chain and (C) LRP1 β chain in brain fractions deprived of capillaries. Data show representative results of 3 to 5 mice per group from experiments performed in triplicate (mean ± SEM). For statistical analyses, unpaired t test was used.