Skip to main content
. 2015 Nov 30;126(1):137–150. doi: 10.1172/JCI81542

Figure 3. Expression of glycolytic and lipogenic genes is impaired in E2f1–/– hepatocytes.

Figure 3

(A) Relative mRNA expression of relevant glycolytic and lipogenic genes in primary hepatocytes from E2f1+/+ and E2f1–/– mice treated for 24 hours with 5 mM low glucose alone (G5); 5 mM low glucose and 100 nM insulin (G5i); or 25 mM high glucose and 100 nM insulin (G25i). (B) Western blot analysis shows expression levels of the indicated proteins in E2f1+/+ and E2f1–/– hepatocytes treated for 24 hours with G5 or G25i. All experiments represent the average of 3 independent experiments. *P < 0.05 compared with control, by 2-tailed, unpaired t test.