Table 3.

Outcome measures from probabilistic tractography using the right MOFC as the seed and all voxels in the brain as the target

	HC (N = 39)	MDD (N = 123)*	F‐test
Weighted FA	.32 ± .03	.32 ± .03	F(1,157) = .32, P = .57
Total number of tracts	2,041,410 ± 575,536	2,030,248 ± 523,381	F(1,155) = .12, P = .73

F‐test includes age, site, and sex as covariates. For total number of tracts, seed size is also included as a covariate. Data are presented as mean ± standard deviation.

FA, fractional anisotropy; HC, healthy control; MDD, major depressive disorder.

*Two subjects were removed for the “total number of tracts” analysis due to extremely high values (>7 million tracts).