Table 3. Univariate logistic regression analysis for association of biomarkers with presence of brain metastasis at baseline.

Biomarkers		N	OR (95%CI)	p-value
CYFRA 21–1
	≤ 3.3 ng/ml	56	1.0
	>3.3 ng/ml	48	1.51 (0.62,3.68)	0.37
NSE
	≤13 ng/ml	86	1.0
	>13 ng/ml	18	0.55 (0.15,2.07)	0.38
ProGRP
	≤50 pg/ml	38	1.0
	>50 pg/ml	9	0.27 (0.03,2.42)	0.24
SCCL-Ag
	≤2.0 ng/ml	96	1.0
	>2.0 ng/ml	8	0.41 (0.05,3.46)	0.41
HE4
	≤65 pmol/L	28	1.0
	>65 pmol/L	76	0.78 (0.29,2.06)	0.61