Fig. 4. (A) IGFBP2, (B) IGFBP3, and (C) IGFBP4 blood concentrations (mean ± SE) of P and respective NP and NC. Results of the SAS mixed model indicating significant (p < 0.05) differences regarding the fixed effects group, time and group × time are shown in the table. Different letters (a, b) indicate significant differences between P, NP, and NC.