Table 1.

Clinical evaluation of affected family members with Axenfeld–Rieger syndrome

Affected family members		V:1	V:2	VI:3	VI:5
Current age (years)		55	60	10	20
Gender		F	M	M	F
Eye
	Iris dysplasia (goniodysgenesis)	+	+	+	+
	Iris hypoplasia	+	+	+	+
	Glaucoma	+	+	+	+
	Early development of nuclear cataract	−	−	+	−
	Polycoria	−	−	+	+
	Corectopia (displaced pupils)	+	+	+	+
	Megacornea	−	−	−	+
	Cataract	−	−	+	−
	Telecanthus	−	−	+	+
	Vitreous condensation	+	+	+	+
Ear
	Abnormal ear, hearing defect	+	+	−	−
Nose
	Broad nasal bridge	+	+	+	+
Teeth
	Microdontia	−	+	+	−
	Micrognathia	+	+	+	−
Abdomen
	Umbilical defect (redundant periumbilical skin)	+	+	−	+
Joints
	Congenital hip anomalies	+	+	−	−