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. 2015 Dec 15;6(6):e01302-15. doi: 10.1128/mBio.01302-15

FIG 1 .

FIG 1 

Simulations of background selection without recombination. (A) Estimates of effective population size (Ne), as a function of actual population size (N). Note the log on the x axis. Ne was predicted theoretically by using the coalescent (28) or coarse-grained transformation to match smaller simulations (24). The coarse-grained approach was only possible for up to 2 × 106 individuals. Ne was also estimated from simulations with 106 to 109 individuals, based on either the average diversity at a neutral site, π, or the frequency of deleterious background alleles, fdel. (B) The effectiveness of selection on a focal allele in the presence of background selection. The x axis shows the selection coefficient of the focal allele (note the log scale), and the y axis shows the average frequency of the deleterious allele at that site. The curve shows the theoretical expectation given Ne (as estimated using diversity at a neutral site). In both panels, the vertical bars show 95% confidence intervals.