Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 14;157(1):346–357. doi: 10.1210/en.2015-1630

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article has been published under the terms of the Creative Commons Attribution License (CC-BY; https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright for this article is retained by the author(s).

PMC Copyright notice

Figure 3. — Global, but not cardiovascular, 11β-HSD1 deficiency reduces LV dilatation, loss of contractile function, and pulmonary edema after MI. Structural (A) and functional (B) remodeling was compared by MRI in WT and global 11β-HSD1-deficient mice (hsd11b1^−/−) and in mice with cardiomyocyte and vascular smooth muscle-specific deletion (hsd11b1^CVCre+) and respective floxed control (hsd11b1^CVCre−) at 8 weeks after induction of MI by CAL. The middle panels show 4 chamber views collected by cine-MRI at end-systole (top) and end-diastole (bottom). Lungs were collected from mice after imaging and weighed to detect pulmonary edema (C). Paired groups were compared by Student's t test; *, P < .05; **, P < .01; ***, P < .005; n = 6–8/group.