Table 1.
List of key selected genes that are regulated by estrogen in cells of innate and adaptive immune system.
| Immune cell | List of genes | Reference |
|---|---|---|
| Neutrophil | CINC-1, CINC-2β, CINC-3, TNFα, IL-6, IL-1β | (8–10) |
| Macrophage | iNOS, NO, IL-6, TNFα | (12–16) |
| Dendritic cells | IL-6, IL-10, CXCL8, CCL2, TGFβ, IL-23, IL-12 | (17, 18, 22) |
| Th1 | IFNγ | (23–25) |
| Th2 | IL-4 | (26) |
| Tregs | FoxP3, PD-1, CTLA-4 | (27–30) |
| B cells | Immunoglobulin, CD22, SHP-1, Bcl-2, VCAM-1 | (31) |