Figure 3.

(A) Coronal [¹²³I]IBZM images of the samt rat in baseline and after challenge with 10 mg/kg L-DOPA/benserazide and benserazide alone. All images show V${}_3^{″}$-values; it is understood, that the calculation of V${}_3^{″}$ is only valid for regions with specific radioligand binding such as the rat striatum. Calculations were performed using PMOD (version 3.5, PMOD Technologies Ltd., Zürich, Switzerland). (B) Striatal equilibrium ratios (V${}_3^{″}$) in baseline and after challenge with 10 mg/kg L-DOPA/benserazide and benserazide alone. Rendered are means and standard deviations of the means. The circles represent the individual animals. For significant differences between conditions the respective p-values are given (two-tailed paired t-test, α = 0.0167 after Bonferroni correction).