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. 2016 Jan 6;36(1):19–30. doi: 10.1523/JNEUROSCI.2856-15.2016

Figure 1.

Figure 1.

P2Y1-targeted siRNA injections into the median and ulnar nerves selectively knock down ischemia-induced protein overexpression in the DRGs. A, Ischemia (BAO or PenCON+BAO) induces an increase in the expression levels of P2Y1 compared with Naive mice and this is prevented by injections of P2Y1-targeted siRNAs (PenY1+BAO) into the ulnar and median nerves 2 d before the ischemic injury. B, Representative Western blot for all conditions assessed showing inhibition of P2Y1 upregulation during BAO or PenCON+BAO by P2Y1-targeting siRNA injections. One-way ANOVA/Tukey's post hoc, *p < 0.01 versus Naive and PenY1+BAO.