Table 3.
Row | Figure | Experiment | n | Variable 1 | Variable 2 | Interaction | Subject matching |
---|---|---|---|---|---|---|---|
1 | 3A | CFA | 9 | Time (CFA) | Side | p < 0.0001 | p < 0.0001 |
p < 0.0001 | p < 0.0001 | F(7,112) = 18.10 | F(16,112) = 7.30 | ||||
F(7,112) = 18.66 | F(1,16) = 30.49 | ||||||
2 | 3B | CFA, BRL44408 0.3 nmol | 6 | Time (BRL44408) | Side | p = 0.75 | p < 0.0001 |
p = 0.0064 | p = 0.93 | F(5,50) = 0.53 | F(10,50) = 6.25 | ||||
F(5,50) = 3.69 | F(1,10) = 0.007 | ||||||
3 | 3C | CFA, BRL44408 3 nmol | 9 | Time (BRL44408) | Side | p = 0.17 | p < 0.0001 |
p < 0.0001 | p = 0.25 | F(5,80) = 1.60 | F(16,80) = 3.88 | ||||
F(5,80) = 19.34 | F(1,16) = 1.43 | ||||||
4 | 3D | saline | 8 | Time (saline) | Side | p = 0.92 | p < 0.0001 |
p = 0.018 | p = 0.78 | F(7,98) = 0.36 | F(14,98) = 13.1 | ||||
F(7,98) = 2.56 | F(1,14) = 0.08 | ||||||
5 | 3E | saline (BRL 44408) | 8 | Time (BRL44408) | Side | p = 0.73 | p < 0.0001 |
p = 0.033 | p = 0.72 | F(6,84) = 0.60 | F(14,84) = 12.1 | ||||
F(6,84) = 2.42 | F(1,14) = 0.14 | ||||||
6 | 4A | CFA | 11 | Time (CFA) | Side | p < 0.0001 | p < 0.0001 |
p < 0.0001 | p = 0.0001 | F(7,140) = 21.1 | F(20,140) = 12.8 | ||||
F(7,140) = 23.15 | F(1,20) = 22.94 | ||||||
7 | 4B | CFA, naltrindole i.th. | 11 | Time (naltrindole) | Side | p = 0.87 | p = 0.0007 |
p = 0.0088 | p = 0.22 | F(5,100 = 0.36 | F(20,100 = 2.66 | ||||
F(5,100) = 3.28 | F(1,20) = 1.60 | ||||||
8 | 4C | CFA, naltrindole s.c. | 8 | Time (naltrindole) | Side | p = 0.14 | p < 0.0001 |
p = 0.0033 | p = 0.97 | F(5,70) = 1.72 | F(14,70) = 8.34 | ||||
F(5,70) = 3.93 | F(1,14) = 0.0017 | ||||||
9 | 4D | saline | 8 | Time (saline) | Side | p = 0.30 | p < 0.0001 |
p = 0.0001 | p = 0.71 | F(7,98) = 1.22 | F(14,98) = 7.66 | ||||
F(7,98) = 4.7 | F(1,14) = 0.15 | ||||||
10 | 4E | saline, naltrindole s.c. | 8 | Time (naltrindole) | Side | p = 0.75 | p = 0.006 |
p = 0.49 | p = 0.022 | F(5,70) = 0.53 | F(14,70) = 2.51 | ||||
F(5,70) = 0.89 | F(1,14) = 6.6 |
Each panel in Figure 3 or 4 (indicated in the second column) was analyzed independently by two-way ANOVA. In the fourth column, n is the number of animals in the experiment. In the fifth and sixth columns, the variable is identified first: “time” refers to the time after the injection of the compound in parentheses; “side” is ipsilateral versus contralateral paw. Subscript numbers in the F ratio are the degrees of freedom and the residual.