Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 1;30(1):52–63. doi: 10.1101/gad.271130.115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Cheung et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genes & Development, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Figure 3. — TIGAR expression is regulated by ROS. (A) MDA staining of small intestines from wild-type (WT), Ahcre⁺Apc^fl/fl, and Ahcre⁺Apc^fl/flMyc^fl/fl 3 d after cre induction. (B) mRNA expression of TIGAR, cyclin D1, HO-1, and p21 from normal wild-type intestinal crypt cultures after 24 h of the indicated ROS treatments. (*) P < 0.05 compared with untreated. n = 3. (C) mRNA expression of TIGAR, cyclin D1, and HO-1 from Apc^min/+ organoid cultures after 24 h of the indicated ROS treatments. (*) P < 0.05 compared with untreated. n = 3. (D) mRNA expression of TIGAR, cyclin D1, and HO-1 from Apc^min/+ organoid cultures after 24 h of the indicated anti-ROS treatments. Bars, 100 µm.