Table 2. Genes included in the TruSeq Amplicon-Cancer Panel (Illumina).
ABL1 | AKT1 | ALK | APC | ATM | BRAF | CDH1 | CDKN2A |
---|---|---|---|---|---|---|---|
CSF1R | CTNNB1 | EGFR | ERBB2 | ERBB4 | FBXW7 | FGFR1 | FGFR2 |
FGFR3 | FLT3 | GNA11 | GNAQ | GNAS | HNF1A | HRAS | IDH1 |
JAK2 | JAK3 | KDR | KIT | KRAS | MET | MLH1 | MPL |
NOTCH1 | NPM1 | NRAS | PDGFRA | PIK3CA | PTEN | PTPN11 | RB1 |
RET | SMAD4 | SMARCB1 | SMO | SRC | STK11 | TP53 | VHL |
The panel consists of 2 × 212 probes covering 221 mutation hot spots in 48 genes known to be important in human cancerogenesis.