Table 4. Prognostic value of PET metrics – multivariate analysis.
| Hazard ratio for OS (P-value) (number of patients) | Hazard ratio for LRFS (P-value) (number of patients) | Hazard ratio for DFS (P-value) (number of patients) | Hazard ratio for DMFS (P-value) (number of patients) | |
|---|---|---|---|---|
| Baseline SUVmax | NS (n=51) | 1.09 (P=0.012) (n=46) | NS (n=51) | 1.08 (P=0.031) (n=51) |
| Post-induction CT SUVmax | NS (n=40) | NS (n=36) | NS (n=40) | 1.11 (P=0.046) (n=40) |
| Post-CRT SUVmax | Not applicable | Not applicable | Not applicable | Not applicable |
| Baseline MTV | NS (n=51) | NS (n=46) | NS (n=51) | NS (n=51) |
| Post-induction CT MTV | NS (n=40) | NS (n=36) | NS (n=40) | NS (n=40) |
| Post-CRT MTV | Not applicable | Not applicable | Not applicable | Not applicable |
Abbreviations: CT=chemotherapy; CRT=chemoradiotherapy; DFS=disease-free survival; DMFS=distant metastasis-free survival; LRFS=local recurrence-free survival; MTV=metabolic tumour volume; NS=not significant; OS=overall survival; PET=positron emission tomography; SUVmax=maximum standard uptake value.