Table 5.

Diagnostic performance of CEUS in characterization of HCC ≤5 cm using differentiation criteria

	AUC	Sensitivity (%)	Specificity (%)	Accuracy (%)
Criteria 1	0.529	87.9	17.9	68.1
Criteria 2	0.778	86.4	69.2	81.5
Criteria 3	0.808	64.1	97.4	73.6

Criteria 1: Arterial hyperenhancement with portal or late phase contrast washout.

Criteria 2: Criteria 1 together with no peripheral rim-like enhancement.

Criteria 3: Criteria 2 together with washout later than 43 seconds

Criteria 1 vs Criteria 2: p<0.001

Criteria 1 vs Criteria 3: p<0.001

Criteria 2 vs Criteria 3: p=0.263

AUC=Area Under Curve